Low AMH: Symptoms, Causes & Treatment Options
Anti-Müllerian Hormone (AMH) is a vital marker of ovarian reserve—the number of eggs a woman has left. AMH is produced by the follicles in the ovaries and can be tested anytime during the menstrual cycle, as its levels remain stable. A healthy AMH range is typically between 2.5 to 4.5 ng/mL.
Symptoms of Low AMH
Low AMH often shows no outward signs and is usually identified during fertility testing. However, some women may experience:
- Irregular menstrual cycles (shorter or longer than usual)
- Spotting before periods
- Hot flashes
- Mood swings
Low AMH is most common after age 35 and progresses more rapidly after age 38. However, about 10% of women experience low AMH levels earlier than expected.
Common Causes of Low AMH
While age is the leading factor, other contributors include:
- Smoking
- Endometriosis
- Radiation or chemotherapy
- Toxic chemical exposure
- Previous ovarian surgeries
- Unexplained (idiopathic) ovarian decline
Treatment for Low AMH
If you’re trying to conceive with low AMH, time is crucial. Early action can improve outcomes. Treatment options include:
- IVF or ICSI with own eggs using personalized stimulation protocols
- Hormonal support with DHEA, testosterone gel, or Vitamin D3 (under medical guidance)
- Intra-ovarian PRP (Platelet-Rich Plasma) or stem cell therapy (experimental treatments with ongoing research)
- Donor eggs if ovarian response is inadequate
Lifestyle & Prevention Tips
Though natural aging is unavoidable, certain steps may help slow the decline of AMH:
- Avoid smoking and harmful substances
- Follow a balanced, nutrient-rich diet
- Stay physically active
- Manage stress levels
- Regular health checkups and fertility screenings
